MADE SAFE screens finished products against a database of known toxic chemicals, checking for behavioral toxins, carcinogens, developmental/reproductive toxins, endocrine disruptors, fire retardants, heavy metals, high-risk pesticides, neurotoxins, and toxic solvents. Products must also pass an ecosystem safety review to ensure ingredients are not bioaccumulative or persistent in aquatic and terrestrial environments. Every ingredient in a product must clear screening — there is no threshold allowance.