In lab tests on human skin cells, willow bark extract reduced inflammatory markers (IL-1α, IL-6, IL-8) and helped restore wound healing when cells were stressed. It also influenced growth factors linked to skin repair. The effect varied depending on whether willow bark was used alone or combined with another ingredient (1,2-decanediol), so real-world results would depend on formulation.

Researchers grew human skin cells in a lab and exposed them to a bacterial component that mimics acne-related inflammation. They then treated some cells with willow bark extract (with and without a helper ingredient) and measured how well the cells recovered.

Funding not disclosed in abstract