In lab tests on human skin cells, willow bark extract reduced inflammatory responses triggered by bacterial lipopolysaccharides—specifically lowering production of inflammatory molecules (IL-1α, IL-6, IL-8) and helping skin cells recover wound-healing ability. The extract worked both alone and combined with a humectant ingredient, suggesting potential benefits for acne-prone skin, though these are early-stage lab results, not real-world skin testing.

Researchers exposed human skin cells (keratinocytes) to bacterial compounds that mimic acne inflammation, then treated them with willow bark extract to measure changes in cell survival, inflammation markers, and healing responses using standardized lab protocols.

Funding not disclosed in abstract