Octocrylene is safe to use in cosmetics at concentrations up to 10%, according to this safety review. Earlier concerns about it disrupting hormones weren't supported by the data, though it can cause photoallergic reactions in some people (usually triggered by sun exposure after using certain pain relievers like ketoprofen). It's a rare allergen overall and works well with other UV filters.
Researchers reviewed existing safety data on octocrylene from the European Chemical Agency and peer-reviewed scientific studies to assess its potential risks when used as a UV filter in cosmetics.
Funding not disclosed in abstract