Octocrylene is safe to use in cosmetics at concentrations up to 10%, according to this European safety review. It doesn't disrupt hormones like some worried it might, though it can occasionally trigger photoallergic reactions (usually linked to sun exposure after applying products with the ingredient ketoprofen). It's a rare skin sensitizer overall and works well paired with other UV filters like avobenzone.
The researchers reviewed safety data from the European Chemical Agency's official database plus peer-reviewed scientific studies to assess octocrylene's effects on skin health and hormones.
Funding not disclosed in abstract