Urea is a naturally occurring ingredient that strengthens your skin's moisture barrier. At concentrations of 10% or less, it works as a gentle moisturizer; above 10%, it actually exfoliates dead skin cells. It's also effective when combined with anti-inflammatory or anti-fungal treatments because it helps those ingredients penetrate better.
This was a review study that analyzed existing clinical research on urea's effects on skin health and various skin conditions like dryness, eczema, and psoriasis.
Funding not disclosed in abstract