Review
Safety Assessment of Mannitol, Sorbitol, and Xylitol as Used in Cosmetics.
Priya Cherian, Wilma F Bergfeld, Donald V Belsito, Curtis D Klaassen, Daniel C Liebler, James G Marks + 6 more
ReviewInternational journal of toxicology2025
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Research Facts
Safety Assessment of Mannitol, Sorbitol, and Xylitol as Used in Cosmetics.
Priya Cherian, Wilma F Bergfeld, Donald V Belsito, Curtis D Klaassen, Daniel C Liebler, James G Marks + 6 more
Review · Moderate · 2025 · International journal of toxicology
Findings

Three sugar alcohols—mannitol, sorbitol, and xylitol—were deemed safe for use in cosmetics at current concentrations. These ingredients work as humectants (they draw moisture to skin) and skin conditioners, and the expert panel found no safety concerns with how they're being used in beauty products right now.

Design: Review
Evidence: Moderate
Journal: International journal of toxicology
Methodology

The Cosmetic Ingredient Safety Expert Panel reviewed available safety data on these three sugar alcohols to assess whether they're safe at the levels and in the ways they're currently used in cosmetic products.

Funded By

Funding not disclosed in abstract