Review
Air-oxidized linalool: a frequent cause of fragrance contact allergy.
Johanna Bråred Christensson, Klaus E Andersen, Magnus Bruze, Jeanne D Johansen, Begoña Garcia-Bravo, Ana Gimenez Arnau + 3 more
ReviewContact dermatitis2012
Research Facts
Air-oxidized linalool: a frequent cause of fragrance contact allergy.
Johanna Bråred Christensson, Klaus E Andersen, Magnus Bruze, Jeanne D Johansen, Begoña Garcia-Bravo, Ana Gimenez Arnau + 3 more
Review · Moderate · 2012
Findings

About 7% of people with dermatitis had allergic reactions to oxidized linalool, a breakdown product of linalool (a common fragrance ingredient). The study found that while pure linalool is safe, it oxidizes when exposed to air, and those oxidized byproducts are what actually trigger allergies—meaning your fragrance exposure matters as much as the ingredient itself.

Design
Review
Evidence
Moderate
Journal
Contact dermatitis
Methodology

Researchers tested nearly 2,900 dermatitis patients across six countries (Denmark, UK, Singapore, Spain, Sweden, Australia) using a standardized patch test with oxidized linalool to see who reacted to it.

Funded By

Funding not disclosed in abstract