Cohort
Novel Formulation of Undecylenic Acid induces Tumor Cell Apoptosis.
Zoe I Day, Alyce J Mayfosh, Marie-Claire Giel, Yuning Hong, Scott A Williams, Jascinta P Santavanond + 3 more
CohortInternational journal of molecular sciences2022
Research Facts
Novel Formulation of Undecylenic Acid induces Tumor Cell Apoptosis.
Zoe I Day, Alyce J Mayfosh, Marie-Claire Giel, Yuning Hong, Scott A Williams, Jascinta P Santavanond + 3 more
Cohort ยท Moderate ยท 2022
Findings

Researchers tested a new formulation of undecylenic acid (a fatty acid already used as an antifungal) combined with L-Arginine and found it killed cancer cells in lab tests by triggering a specific cell death pathway. The compound worked in a dose-dependent way, meaning higher concentrations were more effective, and it bypassed the cell's usual protective mechanisms against fatty acids.

Design
Cohort
Evidence
Moderate
Journal
International journal of molecular sciences
Methodology

Scientists created a new way to dissolve undecylenic acid using amino acids, then tested this formulation on tumor cells in a lab setting to understand how it worked at the cellular level.

Funded By

Funding not disclosed in abstract