A 6-month study of 73 people with diabetic nerve damage found that a supplement combo (containing SOD, alpha lipoic acid, B vitamins, and minerals) reduced pain scores by about 33% and improved nerve function markers like vibration sensation and nerve conduction speed. The placebo group saw no improvement in pain and actually experienced worsening nerve damage, making the difference between groups statistically significant.

Researchers randomly assigned 73 people with type 2 diabetes and nerve damage to either take the supplement combo (2 tablets daily) or placebo for 6 months, measuring pain, nerve function, and quality of life markers throughout.

Funding not disclosed in abstract