Review
Safety Assessment of Diethanolamine and Its Salts as Used in Cosmetics.
Monice M Fiume, Bart Heldreth, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen + 6 more
ReviewInternational journal of toxicology2017
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Research Facts
Safety Assessment of Diethanolamine and Its Salts as Used in Cosmetics.
Monice M Fiume, Bart Heldreth, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen + 6 more
Review · Moderate · 2017 · International journal of toxicology
Findings

Diethanolamine (a pH balancer) and its 16 salt derivatives are considered safe in cosmetics when they don't irritate skin. The key catch: these ingredients can't be used in formulas where N-nitroso compounds might form, since that combination raises safety concerns.

Design: Review
Evidence: Moderate
Journal: International journal of toxicology
Methodology

The Cosmetic Ingredient Review Expert Panel evaluated existing animal and human safety data on diethanolamine and its salts, relying on previous research reports since not every individual salt had its own study.

Funded By

Funding not disclosed in abstract