RCT
Effect of dietary supplementation with omega-3 fatty acid and gamma-linolenic acid on acne vulgaris: a randomised, double-blind, controlled trial.
Jae Yoon Jung, Hyuck Hoon Kwon, Jong Soo Hong, Ji Young Yoon, Mi Sun Park, Mi Young Jang + 1 more
RCTActa dermato-venereologica2014n=45
Research Facts
Effect of dietary supplementation with omega-3 fatty acid and gamma-linolenic acid on acne vulgaris: a randomised, double-blind, controlled trial.
Jae Yoon Jung, Hyuck Hoon Kwon, Jong Soo Hong, Ji Young Yoon, Mi Sun Park, Mi Young Jang + 1 more
RCT ยท Strong ยท 2014
Findings

After 10 weeks, people taking omega-3 supplements (2,000 mg) or gamma-linolenic acid from borage oil (400 mg) saw significant decreases in both inflammatory and non-inflammatory acne lesions compared to a control group. Skin biopsies showed reduced inflammation and lower levels of interleukin-8, a protein that drives acne. No serious side effects were reported.

Design
RCT
Sample
n=45
Evidence
Strong
Journal
Acta dermato-venereologica
Methodology

45 people with mild to moderate acne were split into three groups: one taking omega-3 fatty acids, one taking gamma-linolenic acid, and one taking nothing. Researchers tracked lesion counts, patient feedback, and skin samples over 10 weeks.

Funded By

Funding not disclosed in abstract