This review examined how coumarins—naturally occurring compounds found in plants—work in the body, particularly their ability to thin blood by blocking vitamin K processing. Researchers explored both pharmaceutical coumarins (like warfarin) used clinically and newer natural versions, noting they have antioxidant and anti-inflammatory properties beyond blood thinning. The study emphasizes that while these compounds have real benefits, overdosing carries serious risks.

This was a literature review that synthesized existing research on coumarin compounds—both pharmaceutical and natural—examining their biochemical mechanisms, chemical structures, and clinical applications.

Funding not disclosed in abstract