This review found that licorice extract shows promise for treating hyperpigmentation and dark spots, though the evidence is mixed. While lab studies support its potential, there are only a few small clinical trials proving it actually works on real skin—so it's not as well-proven as some other options like soy or niacinamide.
Researchers reviewed published studies on natural ingredients used for skin lightening, comparing what lab tests showed versus what actual clinical trials on people demonstrated.
Funding not disclosed in abstract