Zinc pyrithione is an antifungal that works by targeting Malassezia yeast on your scalp—the main culprit behind dandruff and seborrheic dermatitis. It's effective at concentrations as low as 10-15 ppm and has been used safely in shampoos for decades because it balances real results with low toxicity risk.

This was a review study that analyzed existing research on how zinc pyrithione works pharmacologically, how it's delivered to skin, and what we know about its safety profile from toxicology studies.

Funding not disclosed in abstract