Review
α-(-)-bisabolol reduces pro-inflammatory cytokine production and ameliorates skin inflammation.
Anil K Maurya, Monika Singh, Vijaya Dubey, Suchita Srivastava, Suaib Luqman, Dnyaneshwar U Bawankule
ReviewCurrent pharmaceutical biotechnology2014
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Research Facts
α-(-)-bisabolol reduces pro-inflammatory cytokine production and ameliorates skin inflammation.
Anil K Maurya, Monika Singh, Vijaya Dubey, Suchita Srivastava, Suaib Luqman, Dnyaneshwar U Bawankule
Review · Moderate · 2014 · Current pharmaceutical biotechnology
Findings

Bisabolol reduced two major inflammatory markers (TNF-alpha and IL-6) in lab and animal models. When applied topically on mouse skin, it decreased inflammation, swelling, and tissue damage in a dose-dependent way, with no safety concerns noted.

Design: Review
Evidence: Moderate
Journal: Current pharmaceutical biotechnology
Methodology

Researchers tested bisabolol in lab cells, on inflamed mouse ears, and used computer modeling to see how it binds to inflammatory proteins.

Funded By

Funding not disclosed in abstract