Review
Grape Seed Oil Microemulsion for Improved Skin Delivery of Resveratrol.
Marianne A P C Nogueira, Camila O Cardoso, Lucas F F Albuquerque, Marcilio Cunha-Filho, Tais Gratieri, Guilherme M Gelfuso
ReviewAAPS PharmSciTech2025
Research Facts
Grape Seed Oil Microemulsion for Improved Skin Delivery of Resveratrol.
Marianne A P C Nogueira, Camila O Cardoso, Lucas F F Albuquerque, Marcilio Cunha-Filho, Tais Gratieri, Guilherme M Gelfuso
Review ยท Moderate ยท 2025
Findings

Researchers created a grape seed oil microemulsion that delivered resveratrol (an antioxidant compound) 4x deeper into skin compared to a basic solution. The formulation stayed stable for 60 days at room temperature and passed safety tests, making it a candidate for treating inflammatory skin conditions.

Design
Review
Evidence
Moderate
Journal
AAPS PharmSciTech
Methodology

Scientists mixed grape seed oil with water and surfactants in specific ratios, then tested how well the resulting microemulsion penetrated pig skin and whether it was safe for topical use.

Funded By

Funding not disclosed in abstract