Review
Grape Seed Oil Microemulsion for Improved Skin Delivery of Resveratrol.
Marianne A P C Nogueira, Camila O Cardoso, Lucas F F Albuquerque, Marcilio Cunha-Filho, Tais Gratieri, Guilherme M Gelfuso
ReviewAAPS PharmSciTech2025
Research Facts
Grape Seed Oil Microemulsion for Improved Skin Delivery of Resveratrol.
Marianne A P C Nogueira, Camila O Cardoso, Lucas F F Albuquerque, Marcilio Cunha-Filho, Tais Gratieri, Guilherme M Gelfuso
Review · Moderate · 2025
Findings

Researchers created a grape seed oil microemulsion that delivered resveratrol (an anti-inflammatory compound) four times deeper into skin compared to a basic solution. The formulation stayed stable for 60 days at room temperature and passed safety tests, making it a potential option for treating inflammatory skin conditions—though human trials haven't happened yet.

Design
Review
Evidence
Moderate
Journal
AAPS PharmSciTech
Methodology

Scientists developed two microemulsion formulas with different water and oil ratios, then tested how well resveratrol penetrated pig skin samples and checked for safety using lab-based irritation tests.

Funded By

Funding not disclosed in abstract