Review
Uptake and bioconversion of alpha-tocopheryl acetate to alpha-tocopherol in skin of hairless mice.
E P Norkus, G F Bryce, H N Bhagavan
ReviewPhotochemistry and photobiology1993
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Research Facts
Uptake and bioconversion of alpha-tocopheryl acetate to alpha-tocopherol in skin of hairless mice.
E P Norkus, G F Bryce, H N Bhagavan
Review · Moderate · 1993 · Photochemistry and photobiology
Findings

When vitamin E acetate was applied topically to mouse skin, it got absorbed and converted into active vitamin E (alpha-tocopherol)—the form that actually works as an antioxidant. The conversion happened significantly more when skin was exposed to UV-B radiation, suggesting sun exposure may actually help your skin utilize this ingredient better.

Design: Review
Evidence: Moderate
Journal: Photochemistry and photobiology
Methodology

Researchers applied vitamin E acetate to hairless mice daily and measured how much accumulated in their skin, with some groups exposed to UV-B rays and others kept in the dark. They tracked both the acetate form and the converted active vitamin E form.

Funded By

Funding not disclosed in abstract