Review
Limonene and linalool hydroperoxides review: Pros and cons for routine patch testing.
Isabel A Ogueta, Johanna Brared Christensson, Elena Giménez-Arnau, Richard Brans, Mark Wilkinson, Luca Stingeni + 5 more
ReviewContact dermatitis2022
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Research Facts
Limonene and linalool hydroperoxides review: Pros and cons for routine patch testing.
Isabel A Ogueta, Johanna Brared Christensson, Elena Giménez-Arnau, Richard Brans, Mark Wilkinson, Luca Stingeni + 5 more
Review · Moderate · 2022 · Contact dermatitis
Findings

Linalool is a common fragrance ingredient that can break down into irritating compounds called hydroperoxides when exposed to air or light. When researchers patch-tested these oxidized forms on people with dermatitis, they found high rates of allergic reactions—yet linalool hydroperoxides aren't routinely screened in Europe, meaning people with sensitivities might not know they're reacting to this specific ingredient.

Design: Review
Evidence: Moderate
Journal: Contact dermatitis
Methodology

This was a literature review examining existing patch test studies on linalool hydroperoxides. Researchers analyzed data from multiple dermatology studies to assess how often these oxidized forms trigger allergic reactions and whether they should be added to standard allergy testing panels.

Funded By

Funding not disclosed in abstract