Researchers tested pomegranate extract in a specially formulated gel on mice with skin tumors and found it had statistically significant anticancer effects compared to untreated controls. The study used nanoparticle technology to help the pomegranate extract penetrate skin more effectively. However, this was animal testing—human efficacy hasn't been established.

Scientists created a pomegranate extract gel using solid lipid nanoparticles (tiny fat-based particles designed for better skin penetration) and tested it on mice with Ehrlich ascites carcinoma tumors. They measured how well the formula moved through skin and compared its anticancer effects against untreated mice.

Funding not disclosed in abstract