Review
Efficacy of pomegranate extract loaded solid lipid nanoparticles transdermal emulgel against Ehrlich ascites carcinoma.
Mahmoud H Teaima, Noha M Badawi, Dalia A Attia, Mohamed A El-Nabarawi, Mohey M Elmazar, Shaker A Mousa
ReviewNanomedicine : nanotechnology, biology, and medicine2022
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Research Facts
Efficacy of pomegranate extract loaded solid lipid nanoparticles transdermal emulgel against Ehrlich ascites carcinoma.
Mahmoud H Teaima, Noha M Badawi, Dalia A Attia, Mohamed A El-Nabarawi, Mohey M Elmazar, Shaker A Mousa
Review · Moderate · 2022 · Nanomedicine : nanotechnology, biology, and medicine
Findings

When pomegranate extract was packaged into tiny nanoparticles and applied to skin as a gel, it showed significant anticancer effects against a specific type of tumor in mice. The nanoparticle delivery method helped the pomegranate penetrate skin more effectively than pomegranate extract alone. This is early-stage lab research—it hasn't been tested on humans yet.

Design: Review
Evidence: Moderate
Journal: Nanomedicine : nanotechnology, biology, and medicine
Methodology

Researchers created a gel formula containing pomegranate extract in nanoparticle form and tested it on mice with skin tumors, comparing results to untreated mice and other control groups. They also studied how well the formula could penetrate mouse skin in lab conditions.

Funded By

Funding not disclosed in abstract