Review
BSA Adsorption on Titanium Dioxide Nanoparticle Surfaces for Controlling Their Cellular Uptake in Skin Cells.
Raweewan Thiramanas, Yodsathorn Wongngam, Goragot Supanakorn, Duangporn Polpanich
ReviewACS applied bio materials2024
vote to see if the hive agrees
Research Facts
BSA Adsorption on Titanium Dioxide Nanoparticle Surfaces for Controlling Their Cellular Uptake in Skin Cells.
Raweewan Thiramanas, Yodsathorn Wongngam, Goragot Supanakorn, Duangporn Polpanich
Review · Moderate · 2024 · ACS applied bio materials
Findings

Researchers modified titanium dioxide nanoparticles (used in sunscreen) by coating them with a protein that reduced how much they penetrate skin by 89-91%. The coated particles still protected against UV damage and DNA damage just as well as regular titanium dioxide, but stayed on the skin surface instead of being absorbed into cells.

Design: Review
Evidence: Moderate
Journal: ACS applied bio materials
Methodology

Scientists tested two types of titanium dioxide nanoparticles—regular ones and ones coated with a protein called BSA—on human skin cells and in lab models of skin penetration. They measured how much each type got absorbed, whether they caused damage, and how well they blocked UV rays.

Funded By

Funding not disclosed in abstract