Pycnogenol French maritime pine bark extract showed benefits for skin health in 39 rigorous clinical trials with 2,009 people total. The extract worked through antioxidant and anti-inflammatory effects, plus it helped strengthen the structural proteins in skin (the extracellular matrix). Results appeared after 2 weeks to 6 months of use.

This is a review of 39 randomized, double-blind, placebo-controlled trials—the gold standard in research. Researchers looked at existing studies to see what Pycnogenol actually did compared to placebo across multiple health areas, including skin.

Funding not disclosed in abstract