Researchers created a hydrogel containing manganese dioxide nanoparticles designed to fight the inflammation and oxidative stress that drives atopic dermatitis. In mouse models with AD, the treatment reduced skin thickening, mast cell buildup, and IgE antibody levels—markers of the condition's severity.
Scientists engineered a hydrogel loaded with hollow manganese dioxide nanoparticles and tested it in lab cells and AD-induced mice to measure its ability to neutralize reactive oxygen species (ROS) and reduce inflammatory markers.
Funding not disclosed in abstract