In wound healing tests, allantoin-infused scaffolds (made from silk fibroin and sodium alginate) closed wounds significantly faster than scaffolds without allantoin or no treatment at all. The material also promoted collagen production, new skin cell growth, and blood vessel formation at the wound site—basically hitting multiple healing markers at once.
Researchers created a transparent gel scaffold with allantoin added to it, then tested how well it worked in lab cell cultures and in mice with cutaneous wounds. They measured wound closure rates, cell behavior, and tissue healing under a microscope.
Funding not disclosed in abstract