Cohort
Allantoin-functionalized silk fibroin/sodium alginate transparent scaffold for cutaneous wound healing.
Haojiang Xie, Qiao Bai, Fankai Kong, Yang Li, Xiaoying Zha, Lingqin Zhang + 4 more
CohortInternational journal of biological macromolecules2022
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Research Facts
Allantoin-functionalized silk fibroin/sodium alginate transparent scaffold for cutaneous wound healing.
Haojiang Xie, Qiao Bai, Fankai Kong, Yang Li, Xiaoying Zha, Lingqin Zhang + 4 more
Cohort · Moderate · 2022 · International journal of biological macromolecules
Findings

In wound healing tests, allantoin-infused scaffolds (made from silk fibroin and sodium alginate) closed wounds significantly faster than scaffolds without allantoin or no treatment at all. The material also promoted collagen production, new skin cell growth, and blood vessel formation at the wound site—basically hitting multiple healing markers at once.

Design: Cohort
Evidence: Moderate
Journal: International journal of biological macromolecules
Methodology

Researchers created a transparent gel scaffold with allantoin added to it, then tested how well it worked in lab cell cultures and in mice with cutaneous wounds. They measured wound closure rates, cell behavior, and tissue healing under a microscope.

Funded By

Funding not disclosed in abstract