Review
Nanoemulsion Containing Kojic Dipalmitate and Rosehip Oil: A Promising Formulation to Treat Melasma.
Júlia Capp Zilles, Larissa Pedron Duarte, Thaís Carine Ruaro, Aline Rigon Zimmer, Irene Clemes Kulkamp-Guerreiro, Renata Vidor Contri
ReviewPharmaceutics2023
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Research Facts
Nanoemulsion Containing Kojic Dipalmitate and Rosehip Oil: A Promising Formulation to Treat Melasma.
Júlia Capp Zilles, Larissa Pedron Duarte, Thaís Carine Ruaro, Aline Rigon Zimmer, Irene Clemes Kulkamp-Guerreiro, Renata Vidor Contri
Review · Moderate · 2023 · Pharmaceutics
Findings

Researchers created a tiny-particle formula (nanoemulsion) combining kojic dipalmitate and rosehip oil that successfully penetrated skin and showed depigmenting power comparable to vitamin C. The formula was stable for at least 30 days when refrigerated, didn't damage skin cells at tested concentrations, and achieved over 95% incorporation efficiency—meaning the active ingredient actually stayed in the formula instead of separating.

Design: Review
Evidence: Moderate
Journal: Pharmaceutics
Methodology

Scientists developed nanoemulsions (super-fine oil-water mixtures) with kojic dipalmitate and rosehip oil, then tested them for stability, ability to penetrate skin layers, antioxidant power, and safety on human cells in lab conditions.

Funded By

Funding not disclosed in abstract