Dodecane
AKA “
n-Dodecane, Dihexyl, Bihexyl, Adakane 12, N-Dodecan, Duodecane, Ba 51-090453
”
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Ingredient Facts
Dodecane
AKA: N-Dodecane, Dihexyl, Bihexyl, Adakane 12, N-Dodecan, Duodecane, Ba 51-090453
Synthetic · Fragrance · EWG: 5
WHAT IS IT?
Synthetic
Fragrance
Solvent
Skin Conditioner
Clean
A lightweight fragrance component derived from ginger and other natural sources, used to create subtle scent in beauty products.
Solubility
less than 1 mg/mL at 77 °F (NTP, 1992)
Formula
C12H26
Mol. Weight
170.33
CAS #
112-40-3
State
N-dodecane is a clear colorless liquid. (NTP, 1992)
See origin →
WHAT'S IT DO?
Functions
Fragrance
Added for scent. Can be natural or synthetic. Common irritant and allergen — one of the top reasons people react to products.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Types
●
all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
IS IT SAFE?
EWG
5
CIR
Insufficient
Pregnancy
—
CIR Safety Findings
all-shades-safe
Regulatory Status
USA
under review
CANADA
✔ permitted
Regulatory Agencies
EWG
CIR
FDA
Health Canada
WHAT'S IT IN?
(2)
The New Skincare Lineup
RMS Beauty
→
True Skin Serum Concealer
ILIA Beauty
→
WHAT'S THE PROOF?
Percutaneous absorption and skin irritation upon low-level prolonged dermal exposure to nonane, dodecane and tetradecane in hairless rats.
Babu RJ, Chatterjee A, Ahaghotu E, Singh M
Toxicology and industrial health, 2004
→
Dihexyl Adipate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Dihexyl Sodium Sulfosuccinate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Dihexyldecyl Adipate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Dihexyldecyl Sebacate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Diisocetyl Dodecanedioate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Dioctyldodecyl Dodecanedioate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Dodecanedioic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Isododecane
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Dioctyldodecyl Dodecanedioate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Dodecane
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Isododecane
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Antitumor efficacy of poly(dimer acid-dodecanedioic acid) copolymer in mice bearing Sarcoma-180 tumor.
Guo WX, Shi Z, Zeng FB, Liang K, Chen XH et al.
Journal of materials science. Materials in medicine, 2007
→
Fragrance material review on ethylene dodecanedioate.
McGinty D, Letizia CS, Api AM
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2011
→
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR