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Ethyl Ferulate
AKA “Ethyl 4-hydroxy-3-methoxycinnamate, ethyl (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate, Ferulic acid, ethyl ester, ORISTRACT EF, NOMCORT EF, NSC-14879, ETHYL 4'-HYDROXY-3'-METHOXYCINNAMAT”
Synthetic
Ingredient Facts
Ethyl ferulate
AKA: Ethyl 4-hydroxy-3-methoxycinnamate, Ethyl (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate, Ferulic acid, Ethyl ester, ORISTRACT EF, NOMCORT EF, NSC-14879, ETHYL 4'-HYDROXY-3'-METHOXYCINNAMAT
Synthetic · Antioxidant · EWG: 5
Synthetic
Sunscreen Filter
Antioxidant
Anti-Aging
Soothing
Skin Conditioner
Synthetic
Clean
A powerful antioxidant that protects skin from environmental damage and free radicals, helping maintain a healthy, youthful appearance.
Formula
C12H14O4
Mol. Weight
222.24
CAS #
4046-02-0
See origin →
Functions
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Anti-Aging
Targets fine lines, wrinkles, or loss of firmness. Works by boosting collagen, speeding cell turnover, or both.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
UV Absorber
Blocks or absorbs UV rays to protect your skin from sun damage, dark spots, and premature aging.
Soothing
Calms redness, irritation, and inflammation. Your skin's chill pill — great for sensitive, reactive, or post-procedure skin.
Neutralizes Free Radicals
Traditional Use
CAS number for Cetyl Alcohol, a fatty alcohol derived from plant or animal sources. Historically used in traditional cosmetics as an emollient and thickening agent before synthetic production became standard in the mid-20th century.
Skin Types
●all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
EWG
5
CIR
Insufficient
Pregnancy
—
CIR Safety Findings
all-shades-safe
Regulatory Status
USAunder review
CANADA✔ permitted
Regulatory Agencies
RIFM fragrance ingredient safety assessment, pentanedioic acid, 1,5-dimethyl ester, CAS Registry Number 1119-40-0.
Api AM, Belsito D, Botelho D, Browne D, Bruze M et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018
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Final Report on the Safety Assessment of Ethyl Ester of PVM/MA Copolymer and Butyl Ester of PVM/MA Copolymer
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
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Ethyl Ester of PVM/MA Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
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Potassium Ethyl Ester of PVM/MA Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
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Shea Butter Ethyl Esters
European Commission
EU Cosmetic Ingredient Database (CosIng)
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Silybum marianum ethyl ester
European Commission
EU Cosmetic Ingredient Database (CosIng)
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Systematic review and technological prospection: ethyl ferulate, a phenylpropanoid with antioxidant and neuroprotective actions.
Cunha FVM, Coelho AG, Azevedo PSDS, da Silva AA Júnior, Oliveira FA et al.
Expert opinion on therapeutic patents, 2019
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Ethyl Ester of PVM/MA Copolymer
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
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Ethyl Ferulate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Ferulic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Shea Butter Ethyl Esters
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
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Detection of fatty acid ethyl esters in skin surface lipids as biomarkers of ethanol consumption in alcoholics, social drinkers, light drinkers, and t
González-Illán F, Ojeda-Torres G, Díaz-Vázquez LM, Rosario O
Journal of analytical toxicology, 2011
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3-Imidazol-4-ylacrylic acid and its ethyl ester
Health Canada
Health Canada Cosmetic Ingredient Hotlist
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Synthesis of mixed esters of ascorbic acid using methyl esters of palm and soybean oils.
Hsieh HJ, Chen JW, Giridhar R, Wu WT
Preparative biochemistry & biotechnology, 2005
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Multifunctional carbomer based ferulic acid hydrogel promotes wound healing in radiation-induced skin injury by inactivating NLRP3 inflammasome.
Huang C, Huangfu C, Bai Z, Zhu L, Shen P et al.
Journal of nanobiotechnology, 2024
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Multifunctional carbomer based ferulic acid hydrogel prom...
Congshu Huang, Chaoji Huangfu, Zhijie Bai, Long Zhu, Pan Shen, Ningning Wang + 5 more
Journal of nanobiotechnology, 2024
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Ferulic acid stabilizes a solution of vitamins C and E an...
Fu-Hsiung Lin, Jing-Yi Lin, Ravindra D Gupta, Joshua A Tournas, James A Burch, M Angelica Selim + 4 more
The Journal of investigative dermatology, 2005
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Formulation and evaluation of a water-in-oil cream containing herbal active ingredients and ferulic acid.
Moldovan M, Lahmar A, Bogdan C, Părăuan S, Tomuţă I et al.
Clujul medical (1957), 2017
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Formulation and evaluation of a water-in-oil cream containing herbal active ingredients and ferulic acid.
Moldovan M, Lahmar A, Bogdan C, Părăuan S, Tomuţă I et al.
Clujul medical (1957), 2017
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Formulation and evaluation of a water-in-oil cream containing herbal active ingredients and ferulic acid.
Moldovan M, Lahmar A, Bogdan C, Părăuan S, Tomuţă I et al.
Clujul medical (1957), 2017
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Stability and Anti-Aging of Encapsulated Ferulic Acid in Phosphorylated Rice Starch.
Pueknang J, Saewan N
Molecules (Basel, Switzerland), 2022
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Stability and Anti-Aging of Encapsulated Ferulic Acid in Phosphorylated Rice Starch.
Pueknang J, Saewan N
Molecules (Basel, Switzerland), 2022
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Antioxidant Properties of Ferulic Acid and Its Possible Application.
Zduńska K, Dana A, Kolodziejczak A, Rotsztejn H
Skin pharmacology and physiology, 2018
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Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR