N,N-Bis(Hydroxyethyl)-p-Phenylenediamine Sulfate
AKA “N-Bis(2-hydroxyethyl)-p-phenylenediamine sulphate, N-Bis(2-hydroxyethyl)-p-phenylenediamine sulfate, COLOREX NNBIS, JAROCOL BHP, (p-Ammoniophenyl)bis(2-hydroxyethyl)ammonium sulphate”
Synthetic
Ingredient Facts
N,n-bis (Hydroxyethyl) -p-phenylenediamine sulfate
AKA: N-Bis(2-hydroxyethyl)-p-phenylenediamine sulphate, N-Bis(2-hydroxyethyl)-p-phenylenediamine sulfate, COLOREX NNBIS, JAROCOL BHP, (p-Ammoniophenyl)bis(2-hydroxyethyl)ammonium sulphate
Synthetic · Colorant · EWG: 4
Synthetic
Colorant
Synthetic
Clean
A gentle hair colorant that delivers rich, lasting color. Commonly used in permanent and semi-permanent hair dyes to create vibrant, even color coverage.
Formula
C10H18N2O6S
Mol. Weight
294.33
CAS #
54381-16-7
Form
Powder
See origin →
Functions
Colorant
Gives the product its color. Purely aesthetic — makes the formula look good in the jar but does nothing for your skin.
Hair Dyeing
Moisturizing
Locks in moisture to keep skin soft and supple throughout the day
Wound Healing
Improves Elasticity
Colors hair
Traditional Use
A synthetic chemical used in oxidative hair dye formulations, developed in the mid-20th century. Created as an intermediate to facilitate permanent hair color development in modern cosmetics.
Skin Types
●all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Caution
Final Report on the Safety Assessment of 2-Methyl-5-Hydroxyethylaminophenol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of Hydroxyethylcellulose, Hydroxypropylcellulose, Methylcellulose, Hydroxypropyl Methylcellulose, and Cellulose Gum
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of N,N-Bis(Hydroxyethyl)-p-Phenylenediamine Sulfate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Re-evaluation: N,N-Bis(2-Hydroxyethyl)-p-Phenylenediamine Sulfate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of 1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate as Used in Cosemtics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of 2-Amino-4-Hydroxyethylaminoanisole and 2-Amino-4-Hydroxyethylaminoanisole Sulfate as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of Hydroxyethyl Urea As Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of Hydroxyethyl-3,4-Methylenedioxyaniline HCl as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of Hydroxypropyl Bis(N-Hydroxyethyl-p-Phenylenediamine) HCl as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
2-Amino-4-Hydroxyethylaminoanisole
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
2-Amino-4-Hydroxyethylaminoanisole Sulfate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
2-Methyl-5-Hydroxyethylaminophenol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
3-Nitro-p-Hydroxyethylaminophenol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR