2-Amino-4-Hydroxyethylaminoanisole
AKA “1-methoxy-2-amino-4-(2-hydroxyethylamino)benzene, RefChem:85205, DTXCID80155108, 2-((3-Amino-4-methoxyphenyl)amino)ethanol, 2-(3-amino-4-methoxyanilino)ethanol
Synthetic
Ingredient Facts
2-Amino-4-Hydroxyethylaminoanisole
AKA: 1-methoxy-2-amino-4-(2-hydroxyethylamino)benzene, RefChem:85205, DTXCID80155108, 2-((3-Amino-4-methoxyphenyl)amino)ethanol, 2-(3-amino-4-methoxyanilino)ethanol
Synthetic · Hair Dyeing · EWG: 5
Synthetic
Synthetic
Clean
A hair color ingredient that helps create rich, long-lasting dye shades. Works as a color developer to achieve vibrant results on hair.
Formula
C9H14N2O2
Mol. Weight
182.22
CAS #
83763-47-7
See origin →
Functions
Hair Dyeing
Colors Hair
Traditional Use
A synthetic hair dye precursor developed mid-20th century for creating reddish and auburn hair colors. It was designed to be more stable and longer-lasting than plant-based alternatives.
Skin Types
all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
No
EWG
5
CIR
Safe w/Qualifications
Pregnancy
No
CIR Safety Findings
ewg-5
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUpermitted
JAPANpermitted
CANADApermitted
Safety Assessment of 2-Amino-4-Hydroxyethylaminoanisole and 2-Amino-4-Hydroxyethylaminoanisole Sulfate as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
2-Amino-4-Hydroxyethylaminoanisole
European Commission
EU Cosmetic Ingredient Database (CosIng)
2-Amino-4-Hydroxyethylaminoanisole Sulfate
European Commission
EU Cosmetic Ingredient Database (CosIng)
2-Amino-4-Hydroxyethylaminoanisole
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
2-Amino-4-Hydroxyethylaminoanisole Sulfate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
2-Amino-4-hydroxyethylaminoanisole sulfate - a coupler causing contact allergy from use in hair dyes.
Madsen JT, Andersen KE
Contact dermatitis, 2016
2-Amino-4-hydroxyethylaminoanisole sulfate - a coupler causing contact allergy from use in hair dyes.
Madsen JT, Andersen KE
Contact dermatitis, 2016
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR