Allantoin
AKA “
Glyoxyldiureide, Cordianine, Glyoxyldiureid, Allantol, Sebical, Alantan, AVC/Dienestrolcream
”
Synthetic
🦆
❤️
👻
Ingredient Facts
Allantoin
AKA: Glyoxyldiureide, Cordianine, Glyoxyldiureid, Allantol, Sebical, Alantan, AVC/Dienestrolcream
Synthetic · Soothing · EWG: 1
WHAT IS IT?
Varies With Manufacturer
Humectant
Soothing
Skin Conditioner
Wound Healer
Synthetic
Clean
A soothing ingredient that calms irritated skin and supports the skin's natural healing process, leaving it feeling soft and comfortable.
Formula
C4H6N4O3
Mol. Weight
158.12
CAS #
97-59-6
Form
Liquid
See origin →
WHAT'S IT DO?
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Soothing
Calms redness, irritation, and inflammation. Your skin's chill pill — great for sensitive, reactive, or post-procedure skin.
Nourishing
Protecting
Skin Types
●
all-skin-types, gentle
Best For
General
Melanin-Rich Skin
Highly Suitable
IS IT SAFE?
EWG
1
CIR
Insufficient
Pregnancy
—
CIR Safety Findings
Not an Irritant
ewg-1
medical-approval
pregnancy-nursing-safe
all-shades-safe
Concentration Guide
2.0%
0%
3%
Reg. Limit
FDA OTC limit (Skin Protectant): 2%. 21 CFR 347.10
Regulatory Status
USA
under review
CANADA
✔ permitted
Regulatory Agencies
EWG
CIR
FDA
Health Canada
WHAT'S THE PROOF?
Final report of the safety assessment of allantoin and its related complexes.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2010
→
Final report of the safety assessment of allantoin and its related complexes.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2010
→
Final report of the safety assessment of allantoin and its related complexes.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2010
→
Final report of the safety assessment of allantoin and its related complexes.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2010
→
Final Report of the Safety Assessment of Allantoin and its Related Complexes
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Allantoin
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Allantoin Ascorbate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Allantoin Biotin
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Allantoin Galacturonic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Allantoin Glycyrrhetinic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Allantoin Panthenol
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Allantoin Polygalacturonic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Allantoin
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Allantoin Glycyrrhetinic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Allantoin Panthenol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Allantoin-functionalized silk fibroin/sodium alginate tra...
Haojiang Xie, Qiao Bai, Fankai Kong, Yang Li, Xiaoying Zha, Lingqin Zhang + 4 more
International journal of biological macromolecules, 2022
→
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR