Allantoin Polygalacturonic Acid
AKA “RefChem:110747, orb1698550, N-(2
Synthetic
Ingredient Facts
Allantoin polygalacturonic acid
AKA: RefChem:110747, Orb1698550, N-(2
Synthetic · Soothing · EWG: 4
Varies With Manufacturer
Soothing
Skin Conditioner
Barrier Support
Wound Healer
Synthetic
Clean
A gentle conditioning agent that helps soothe and protect skin, leaving it softer and more comfortable while supporting its natural barrier.
Formula
C10H16N4O10
Mol. Weight
352.26
CAS #
29659-38-9
Form
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Protecting
Helps rebuild and strengthen your skin barrier — the invisible shield that keeps moisture in and irritants out. Essential after over-exfoliating or harsh weather.
Soothing
Calms redness, irritation, and inflammation. Your skin's chill pill — great for sensitive, reactive, or post-procedure skin.
Nourishing
Protecting
Traditional Use
A synthetic derivative combining allantoin (traditional comfrey compound for healing) with polygalacturonic acid (plant-derived polysaccharide). Developed for enhanced skin film-forming and conditioning in modern cosmetics.
Skin Types
all-skin-types
Best For
Irritation
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Insufficient
Pregnancy
Yes
CIR Safety Findings
Not an Irritant
medical-approval
all-shades-safe
Regulatory Status
USAunder review
EUrestricted
JAPANrestricted
CANADArestricted
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR