Anhydroglucitol
AKA “5-Anhydro-D-glucitol, 5-Anhydroglucitol, 5-Anhydro-D-sorbitol, 5-ANHYDROSORBITOL, Aceritol, (2R, 5S)-2-(hydroxymethyl)oxane-3, D-Glucitol
Synthetic
Ingredient Facts
Anhydroglucitol
AKA: 5-Anhydro-D-glucitol, 5-Anhydroglucitol, 5-Anhydro-D-sorbitol, 5-ANHYDROSORBITOL, Aceritol, (2R, 5S)-2-(hydroxymethyl)oxane-3, D-Glucitol
Synthetic · Humectant · EWG: 4
Synthetic
Humectant
Skin Conditioner
Synthetic
Clean
A natural sugar derived ingredient that deeply hydrates skin while helping to maintain moisture balance. It also supports a healthy-looking complexion by conditioning and nourishing the skin barrier.
Formula
C6H12O5
Mol. Weight
164.16
CAS #
154-58-5
Form
Liquid
State
Solid
See origin →
Functions
Antiplaque
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks In Moisture
Traditional Use
A synthetic polyol developed for cosmetic applications in the late 20th century. Designed as a humectant and skin-conditioning agent to improve moisture retention without the stickiness of glycerin.
Skin Types
all-skin-types
Best For
Dehydration
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
medical-approval
all-shades-safe
Phototoxicity Concern
Concentration Guide
Dermal absorption: 100%. Source: CIR Safety Assessment (CIR Seq 815).
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Safety Assessment of Anhydrogalactose,Anhydroglucitol, Anhydroxylitol, Arabinose,Psicose, Saccharide Hydrolysate, andSaccharide Isomerate as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Anhydroglucitol
European Commission
EU Cosmetic Ingredient Database (CosIng)
Safety Assessment of Anhydrogalactose, Anhydroglucitol, Anhydroxylitol, Arabinose, Psicose, Saccharide Hydrolysate, and Saccharide Isomerate as Used i
Johnson W Jr, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
Safety Assessment of Anhydrogalactose, Anhydroglucitol, Anhydroxylitol, Arabinose, Psicose, Saccharide Hydrolysate, and Saccharide Isomerate as Used i
Johnson W Jr, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR