undefined 1
undefined 2
undefined 3
undefined 4
undefined 5
undefined 6
undefined 7
undefined 8
undefined 9
undefined 10
undefined 11
Ascorbic acid (Vitamin C)
AKA “● L-THREO-HEX-2-ENONIC ACID”
Vitamin C
Ingredient Facts
Ascorbic acid (Vitamin C)
AKA: ● L-THREO-HEX-2-ENONIC ACID
Vitamin C · Antioxidant · EWG: 1
Varies With Manufacturer
Antioxidant
Soothing
Skin Conditioner
Vitamin C
Clean
Vitamin C brightens skin and helps protect against environmental damage with powerful antioxidant benefits.
Formula
C6H8O6
Mol. Weight
176.12
CAS #
50-81-7 / 62624-30-0
Form
Liquid
See origin →
Functions
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Soothing
Calms redness, irritation, and inflammation. Your skin's chill pill — great for sensitive, reactive, or post-procedure skin.
Neutralizes free radicals
Brightens uneven skin tone
Boosts collagen production
Evens pigmentation
Melanin-Rich Skin
Highly Suitable
EWG
1
CIR
—
Pregnancy
—
CIR Safety Findings
ewg-1
pregnancy-nursing-safe
all-shades-safe
Phototoxicity Concern
Regulatory Agencies
Vitamin C (Ascorbic Acid).
Abdullah M, Jamil RT, Attia FN
, 2026
→
Vitamin C (Ascorbic Acid).
Abdullah M, Jamil RT, Attia FN
, 2026
→
Topical Vitamin C and the Skin: Mechanisms of Action and ...
Firas Al-Niaimi, Nicole Yi Zhen Chiang
The Journal of clinical and aesthetic dermatology, 2017
→
Topical Vitamin C in Dermatology
Al-Niaimi F, Chiang NYZ
Journal of Clinical and Aesthetic Dermatology, 2017
→
Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications.
Al-Niaimi F, Chiang NYZ
The Journal of clinical and aesthetic dermatology, 2017
→
Ascorbic Acid (Vitamin C) as a Cosmeceutical to Increase ...
Yong Chool Boo
Antioxidants (Basel, Switzerland), 2022
→
Ascorbic Acid (Vitamin C) as a Cosmeceutical to Increase ...
Yong Chool Boo
Antioxidants (Basel, Switzerland), 2022
→
Ascorbic Acid (Vitamin C) as a Cosmeceutical to Increase Dermal Collagen for Skin Antiaging Purposes: Emerging Combination Therapies.
Boo YC
Antioxidants (Basel, Switzerland), 2022
→
The role of Bromelain and Liposomal Vitamin C in the trea...
Giacomo Buso, Paolo Santini, Francesca Ghirardini, Francesca Cannavacciuolo, Adriana Visonà, Beniamino Zalunardo + 2 more
VASA. Zeitschrift fur Gefasskrankheiten, 2025
→
Extended Re-review Summary: Safety Assessment of Ascorbic Acid and Ascorbates as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Safety Assessment of Ethers and Esters of Ascorbic Acid as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Ascorbic Acid (Vitamin C)
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Ascorbyl Phosphate [Vitamin C]
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and
Elmore AR
International journal of toxicology, 2005
→
Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and
Elmore AR
International journal of toxicology, 2005
→
Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and
Elmore AR
International journal of toxicology, 2005
→
Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and
Elmore AR
International journal of toxicology, 2005
→
Ascorbic Acid (Vitamin C)
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Development of phospholipid nanoparticles encapsulating 3-O-cetyl ascorbic acid and tocopherol acetate (TA-Cassome) for improving their skin accumulat
Fushimi T, Uchino T, Miyazaki Y, Hatta I, Asano M et al.
International journal of pharmaceutics, 2018
→
[Vitamin C and its derivatives in maintaining the good skin condition].
Goik U
Postepy biochemii, 2024
→
Vitamin C-squalene bioconjugate promotes epidermal thicke...
R Gref, C Deloménie, A Maksimenko, E Gouadon, G Percoco, E Lati + 3 more
Scientific reports, 2020
→
Design of Novel Tricaprylin-Incorporated Multi-Layered Liposomal System for Skin Delivery of Ascorbic Acid with Improved Chemical Stability.
Ho MJ, Park DW, Kang MJ
Pharmaceuticals (Basel, Switzerland), 2023
→
Synthesis of mixed esters of ascorbic acid using methyl esters of palm and soybean oils.
Hsieh HJ, Chen JW, Giridhar R, Wu WT
Preparative biochemistry & biotechnology, 2005
→
Vanillic acid and vitamin C attenuated di-2-ethylhexyl ph...
B Ogunlade, S C Gbotolorun, O A Adedotun, K Iteire, J Adejayi
Reproduction & fertility, 2022
→
Topical L-ascorbic acid: percutaneous absorption studies.
Pinnell SR, Yang H, Omar M, Monteiro-Riviere N, DeBuys HV et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2001
→
Topical L-ascorbic acid: percutaneous absorption studies.
Pinnell SR, Yang H, Omar M, Monteiro-Riviere N, DeBuys HV et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2001
→
Topical L-ascorbic acid: percutaneous absorption studies.
Pinnell SR, Yang H, Omar M, Monteiro-Riviere N, DeBuys HV et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2001
→
Roles of Vitamin C in Skin Health
Pullar JM, Carr AC, Vissers MCM
Nutrients, 2017
→
Verified Feb 2026
Data: Kew POWO · PubChem · CosIng · EWG
Ascorbic acid (Vitamin C) — Duck Heart Ghost