Benzophenone-2
AKA “4'-Tetrahydroxybenzophenone, Bis(2, 4-dihydroxyphenyl)methanone, Methanone, bis(2, Uvinol D-50, Uvinul D-50”
Synthetic
Ingredient Facts
Benzophenone-2
AKA: 4'-Tetrahydroxybenzophenone, Bis(2, 4-dihydroxyphenyl)methanone, Methanone, Bis(2, Uvinol D-50, Uvinul D-50
Synthetic · Uv Absorber · EWG: 4
Synthetic
Sunscreen Filter
Synthetic
Clean
Provides UV protection by absorbing harmful sun rays that can damage skin. Helps shield against sun damage and premature aging.
Solubility In water, 8,821 mg/L at 24.99 °C
Formula
C13H10O5
Mol. Weight
246.21
CAS #
131-55-5
Form
Powder
See origin →
Functions
Uv Absorber
Blocks or absorbs UV rays to protect your skin from sun damage, dark spots, and premature aging.
Shields from UV damage
Traditional Use
A synthetic UV absorber developed in the mid-20th century for sunscreen formulations. Engineered to provide broad-spectrum UV protection in cosmetics as part of the modern synthetic alternative to natural sun-protective ingredients.
Skin Types
●all-skin-types
Best For
Sun Damage
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Caution
EWG
4
CIR
Safe w/Qualifications
Pregnancy
Caution
CIR Safety Findings
Not a Sensitizer
ewg-4
medical-approval
all-shades-safe
Concentration Guide
5.0%
0%7%
Reg. Limit
EU/SCCS limit: 5% in cosmetic products. Opinion: SCCS/1679/25
Regulatory Agencies
Benzophenone-2 Concentration and Its Effect on Oxidative Stress and Apoptosis Markers in Rat Brain.
Broniowska Ż, Bystrowska B, Starek-Świechowicz B, Pomierny B, Krzyżanowska W et al.
Neurotoxicity research, 2019
Re-evaluation: N,N-Bis(2-Hydroxyethyl)-p-Phenylenediamine Sulfate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Benzophenone-2
European Commission
EU Cosmetic Ingredient Database (CosIng)
N,N-Bis(2-Hydroxyethyl)-p-Phenylenediamine Sulfate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Benzophenone-2
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
N,N-Bis(2-Hydroxyethyl)-p-Phenylenediamine Sulfate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
N,N-bis(2-Chloroethyl)methylamine N-oxide and its salts
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR