Capryl/Capramidopropyl Betaine
AKA “Capramidopropyl Betaine, CAPB, Surfactant”
Synthetic
Ingredient Facts
Capryl/capramidopropyl betaine
AKA: CAPB, Surfactant
Synthetic · Cleansing · EWG: 5
Synthetic
Cleanser
Skin Conditioner
Hair Care
Plant Oil
Synthetic
Clean
N-(3-Decanoyl(or octanoyl)aminopropyl)-N-carboxymethyl-N,N-dimethyl-1-propanaminium inner salts Science: Functions: Antistatic, Cleansing, Hair Conditioning, Skin Conditioning, Surfactant - Cleansing, Surfactant - Foam Boosting, Viscosity Controlling Safety Ratings: CIR: Safe as used
CAS #
61789-40-0
Form
Liquid
See origin →
Functions
Antistatic
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Foam Boosting
Viscosity Controlling
Locks in moisture
Traditional Use
A synthetic surfactant blend developed in the late 20th century combining caprylic and capric acid derivatives with betaine chemistry. Used as a mild cleansing agent in personal care products.
Skin Types
●all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
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Coacervation in Cationic Polyelectrolyte Solutions with Anionic Amino Acid Surfactants.
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Bárány E, Lindberg M, Lodén M
Contact dermatitis, 1999
Biophysical characterization of skin damage and recovery after exposure to different surfactants.
Bárány E, Lindberg M, Lodén M
Contact dermatitis, 1999
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Langmuir : the ACS journal of surfaces and colloids, 2021
Influence of Oil Polarity and Cosurfactants on the Foamability of Mono- and Diacylphosphatidylcholine Stabilized Emulsions.
Bunk M, Daniels R
Pharmaceutics, 2022
Enhanced stability and skin permeation of ibuprofen-loaded solid lipid nanoparticles based binary solid lipid matrix: Effect of surfactant and lipid c
Chantaburanan T, Teeranachaideekul V, Jintapattanakit A, Chantasart D, Junyaprasert VB
International journal of pharmaceutics: X, 2023
Final Report of the Cosmetic Ingredient Review Expert Panel on the Safety Assessment of Cocamidopropyl Betaine (CAPB)
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Irritant and sensitizing potential of eight surfactants commonly used in skin cleansers: an evaluation of 105 patients.
Corazza M, Lauriola MM, Bianchi A, Zappaterra M, Virgili A
Dermatitis : contact, atopic, occupational, drug, 2010
Irritant and sensitizing potential of eight surfactants commonly used in skin cleansers: an evaluation of 105 patients.
Corazza M, Lauriola MM, Bianchi A, Zappaterra M, Virgili A
Dermatitis : contact, atopic, occupational, drug, 2010
Irritant and sensitizing potential of eight surfactants commonly used in skin cleansers: an evaluation of 105 patients.
Corazza M, Lauriola MM, Bianchi A, Zappaterra M, Virgili A
Dermatitis : contact, atopic, occupational, drug, 2010
Irritant and sensitizing potential of eight surfactants commonly used in skin cleansers: an evaluation of 105 patients.
Corazza M, Lauriola MM, Bianchi A, Zappaterra M, Virgili A
Dermatitis : contact, atopic, occupational, drug, 2010
Interleukin-1 production after treatment with non-ionic surfactants in a murine keratinocytes cell line.
Corsini E, Marinovich M, Marabini L, Chiesara E, Galli CL
Toxicology in vitro : an international journal published in association with BIBRA, 1994
Capryl/Capramidopropyl Betaine
European Commission
EU Cosmetic Ingredient Database (CosIng)
Mild but effective skin cleansing-Evaluation of laureth-23 as a primary surfactant.
Dick A, Stolz HJ, Sonsmann FK
International journal of cosmetic science, 2024
Mild but effective skin cleansing-Evaluation of laureth-23 as a primary surfactant.
Dick A, Stolz HJ, Sonsmann FK
International journal of cosmetic science, 2024
Mild but effective skin cleansing-Evaluation of laureth-23 as a primary surfactant.
Dick A, Stolz HJ, Sonsmann FK
International journal of cosmetic science, 2024
Influence of surfactant on the thermal behavior of marigold oil emulsions with liquid crystal phases.
dos Santos OD, da Rocha-Filho PA
Drug development and industrial pharmacy, 2007
Development, Characterization and Skin Interaction of Capsaicin-Loaded Microemulsion-Based Nonionic Surfactant.
Duangjit S, Chairat W, Opanasopit P, Rojanarata T, Panomsuk S et al.
Biological & pharmaceutical bulletin, 2016
Capryl/Capramidopropyl Betaine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Development of an Auraptene-Loaded Transdermal Formulation Using Non-ionic Sugar Ester Surfactants.
Flores KA, Okada A, Arce F Jr, See GL, Itakura S et al.
Chemical & pharmaceutical bulletin, 2024
Interactions of C12 surfactants with the skin: studies on enzyme release and percutaneous absorption in vitro.
Gibson WT, Teall MR
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1983
The surfactant Dioctyl Sodium Sulfosuccinate (DOSS) exposure causes adverse effects in embryos and adults of zebrafish (Danio rerio).
González-Penagos CE, Zamora-Briseño JA, Améndola-Pimenta M, Pérez-Vega JA, Montero-Muñoz J et al.
Toxicology and applied pharmacology, 2022
Epidemiology and Co-Reactivity of Novel Surfactant Allergens: A Double-Blind Randomized Controlled Study.
Grey KR, Hanson JL, Hagen SL, Hylwa SA, Warshaw EM
Dermatitis : contact, atopic, occupational, drug, 2016
Epidemiology and Co-Reactivity of Novel Surfactant Allergens: A Double-Blind Randomized Controlled Study.
Grey KR, Hanson JL, Hagen SL, Hylwa SA, Warshaw EM
Dermatitis : contact, atopic, occupational, drug, 2016
Epidemiology and Co-Reactivity of Novel Surfactant Allergens: A Double-Blind Randomized Controlled Study.
Grey KR, Hanson JL, Hagen SL, Hylwa SA, Warshaw EM
Dermatitis : contact, atopic, occupational, drug, 2016
Epidemiology and Co-Reactivity of Novel Surfactant Allergens: A Double-Blind Randomized Controlled Study.
Grey KR, Hanson JL, Hagen SL, Hylwa SA, Warshaw EM
Dermatitis : contact, atopic, occupational, drug, 2016
Reaction to cocamidopropyl hydroxysultaine, an amphoteric surfactant and conditioner.
Guin JD
Contact dermatitis, 2000
The Effect of Alkyl Chain Number in Sucrose Surfactant on the Physical Properties of Quercetin-Loaded Deformable Nanoliposome and Its Effect on In Vit
Hong IK, Ha JH, Han S, Kang H, Park SN
Nanomaterials (Basel, Switzerland), 2018
Hydrogel Formation by Glutamic-acid-based Organogelator Using Surfactant-mediated Gelation.
Ikeda N, Aramaki K
Journal of oleo science, 2022
The influence of surfactants and hydrolyzed proteins on keratinocytes viability and elasticity.
Kobiela T, Lelen-Kaminska K, Stepulak M, Lekka M, Malejczyk M et al.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 2013
Role of architecture of N-oxide surfactants in the design of nanoemulsions for Candida skin infection.
Lewińska A, Jaromin A, Jezierska J
Colloids and surfaces. B, Biointerfaces, 2020
Using Microemulsion as Carrier for Drug Transdermal Delivery: The Effect of Surfactants and Cosurfactants.
Lu IJ, Fu YS, Chang WY, Wu PC
Current pharmaceutical design, 2019
Transdermal absorption of natural progesterone from alcoholic gel formulations with hydrophilic surfactant.
Matsui R, Ueda O, Uchida S, Namiki N
Drug development and industrial pharmacy, 2015
Optimizing interactions between soluble silk fibroin and capryl glucoside for design of a natural and high-performance co-surfactant system.
Maxwell R, Costache MC, Giarrosso A, Bosques C, Amin S
International journal of cosmetic science, 2021
Morphological study of cationic polymer-anionic surfactant complex precipitated in solution during the dilution process.
Miyake M, Kakizawa Y
Journal of cosmetic science, 2010
Effect of oil phase lipophilicity on in vitro drug release from o/w microemulsions with low surfactant content.
Montenegro L, Carbone C, Condorelli G, Drago R, Puglisi G
Drug development and industrial pharmacy, 2006
Comparing Surfactant Penetration into Human Skin and Resulting Skin Dryness Using In Vivo and Ex Vivo Methods.
Morris SA, McCardy N, Thompson R, Allen T, Altemeier A et al.
Journal of cosmetic science, 2019
Surfactant Penetration into Human Skin from Sodium Dodecyl Sulfate and Lauramidopropyl Betaine Mixtures.
Morris SAV, Xu L, Ananthapadmanabhan KP, Kasting GB
Langmuir : the ACS journal of surfaces and colloids, 2021
Structure and performance of cationic assembly dispersed in amphoteric surfactants solution as a shampoo for hair damaged by coloring.
Nagahara Y, Nishida Y, Isoda M, Yamagata Y, Nishikawa N et al.
Journal of oleo science, 2007
Biocompatible lecithin-based microemulsions with rhamnolipid and sophorolipid biosurfactants: formulation and potential applications.
Nguyen TT, Edelen A, Neighbors B, Sabatini DA
Journal of colloid and interface science, 2010
Design and Characterization of Silicone and Surfactant Based Systems for Topical Drug Delivery.
Oyafuso MH, Carvalho FC, Chiavacci LA, Gremião MP, Chorilli M
Journal of nanoscience and nanotechnology, 2015
Design and Characterization of Silicone and Surfactant Based Systems for Topical Drug Delivery.
Oyafuso MH, Carvalho FC, Chiavacci LA, Gremião MP, Chorilli M
Journal of nanoscience and nanotechnology, 2015
Influences of added surfactants on the water solubility and antibacterial activity of rosemary extract.
Park S, Mun S, Kim YR
Food science and biotechnology, 2020
Influences of added surfactants on the water solubility and antibacterial activity of rosemary extract.
Park S, Mun S, Kim YR
Food science and biotechnology, 2020
Fatty acid sulphoalkyl amides and esters as cosmetic surfactants.
Petter PJ
International journal of cosmetic science, 1984
Fatty acid sulphoalkyl amides and esters as cosmetic surfactants.
Petter PJ
International journal of cosmetic science, 1984
The History of Surfactants and Review of Their Allergic and Irritant Properties.
Presley CL, Militello M, Barber C, Ladd R, Laughter M et al.
Dermatitis : contact, atopic, occupational, drug, 2021
Structure and rheology of semisolid o/w creams containing cetyl alcohol/non-ionic surfactant mixed emulsifier and different polymers.
Ribeiro HM, Morais JA, Eccleston GM
International journal of cosmetic science, 2004
Polyglycerol fatty acid ester surfactant-based microemulsions for targeted delivery of ceramide AP into the stratum corneum: formulation, characterisa
Sahle FF, Metz H, Wohlrab J, Neubert RH
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2012
Characterization and cytotoxicity assessment of biosurfactant derived from Lactobacillus pentosus NCIM 2912.
Sharma V, Singh D, Manzoor M, Banpurkar AG, Satpute SK et al.
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2022
Antimicrobial Nanoparticles Composed of Zein and Arginine-Phenylalanine-Based Surfactants for Wound Related Infections: Antioxidant and Skin-Related A
Sousa FFO, Hafidi Z, García MT, Moran MDC, Vazquez S et al.
Antibiotics (Basel, Switzerland), 2024
Method for Simultaneous Determination of Amino Acid Surfactants Sodium N-Lauroylsarcosinate and Sodium Methyl Cocoyl Taurate in Personal Care Products
Thangarathinam K, Narayanan U
Journal of chromatographic science, 2025
Method for Simultaneous Determination of Amino Acid Surfactants Sodium N-Lauroylsarcosinate and Sodium Methyl Cocoyl Taurate in Personal Care Products
Thangarathinam K, Narayanan U
Journal of chromatographic science, 2025
Effects of temperature, surfactants and skin location on the dermal penetration of haloacetonitriles and chloral hydrate.
Trabaris M, Laskin JD, Weisel CP
Journal of exposure science & environmental epidemiology, 2012
Prevalence of Surfactant in the Contact Allergen Management Program.
Weinhammer AP, Scheman A, Reeder MJ
Dermatitis : contact, atopic, occupational, drug, 2019
Surfactant-induced skin irritation and skin repair. Evaluation of the acute human irritation model by noninvasive techniques.
Wilhelm KP, Freitag G, Wolff HH
Journal of the American Academy of Dermatology, 1994
Verified Feb 2026
Data: CosIng · EWG · CIR