undefined 1
undefined 2
undefined 3
undefined 4
Ceramide np (N-acylated Phytosphingosine)
AKA “ceramide np, Ceramide 3B, Cytomide IIIa, Cytomide IIIb, Ceramide IIIB”
Synthetic
Ingredient Facts
Ceramide np (N-acylated Phytosphingosine)
AKA: Ceramide 3B, Cytomide IIIa, Cytomide IIIb, Ceramide IIIB
Synthetic · Emollient · EWG: 4
Synthetic
Emollient
Skin Conditioner
Ceramide
Synthetic
Clean
A naturally-derived moisturizer that strengthens your skin's barrier and leaves hair soft and smooth.
CAS #
72968-43-5
Form
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Moisturising
Strengthens skin barrier
Locks in moisture
Prevents moisture loss
Traditional Use
Developed in the 1990s as a synthetic ceramide designed to mimic natural ceramides found in skin barrier lipids. Ceramides were identified as key components of the stratum corneum, and synthetic versions were created to repair compromised skin barriers and reduce transepidermal water loss.
Skin Types
●all-skin-types
Best For
Dryness
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Barrier Repair Cream
Alpyn Beauty
 →
Instant Bright Eye
Alpyn Beauty
 →
Mini Barrier Repair Cream
Alpyn Beauty
 →
peptide fine line eye gel
Cocokind
 →
electrolyte water cream
Cocokind
 →
ceramide lip blur balm
Cocokind
 →
travel-size Electrolyte Water Cream
Cocokind
 →
hydration heroes set
Cocokind
 →
calm & clarify duo
Cocokind
 →
rise + shine trio
Cocokind
 →
ceramide hydration duo
Cocokind
 →
retinol face + body duo
Cocokind
 →
youthful duo
Cocokind
 →
milky-soft face and body cleanser
Cocokind
 →
flavored ceramide lip blur balm
Cocokind
 →
Gentle Genius™ Barrier Care Rapid Rescue Hand Cream
Pai Skincare
 →
Gentle Genius™ Barrier Care Wet Skin Moisturizer
Pai Skincare
 →
Easy Calm, Easy Glow Gift Set
Pai Skincare
 →
Take Your Vitamins Duo
Indie Lee
 →
Super Rich Ceramide + Collagen Firming Cream
Kinship
 →
Hydration Set
Kinship
 →
Glow + Go Set
Kinship
 →
Gentle Body Wash - Unscented
Kinship
 →
Restorative Body Serum - Unscented
Kinship
 →
Restorative Body Serum - Vanilla
Kinship
 →
Moisturizing Body Cream - Unscented
Kinship
 →
Moisturizing Body Cream - Vanilla
Kinship
 →
The Bodycare Ritual - Vanilla
Kinship
 →
The Bodycare Ritual - Unscented
Kinship
 →
The Hydrate + Brighten Ritual
Kinship
 →
Morning + Night Serum Set
Kinship
 →
Black Tulip Facial Treatment
Bloom Effects
 →
Royal Tulip Vitamin C Facial Oil
Bloom Effects
 →
Balance + Support Duo
Marie Veronique
 →
The Lip Balm Duo
Nécessaire
 →
The Hand-Lip Moisture Duo
Nécessaire
 →
The Hand Duo
Nécessaire
 →
The New Tendency Duo
Nécessaire
 →
The New Tendency Complete Set
Nécessaire
 →
The Hand Cream + The Tube Key
Nécessaire
 →
The Body Duo
Nécessaire
 →
The Body Brush
Nécessaire
 →
Alpine Rich Cream | Dry Skin's Dream Come True – Ursa Major Skincare
Ursa Major
 →
Vitamins C+E+Ferulic Serum
Marie Veronique
 →
Supernutrient Firming Facial
Marie Veronique
 →
Gentle Retinol Night Serum
Marie Veronique
 →
Barrier Restore Serum
Marie Veronique
 →
Barrier Lipid Complex
Marie Veronique
 →
Superkind Bio-Barrier Serum
Tata Harper Skincare
 →
Superkind Bio-Barrier Eye Crème
Tata Harper Skincare
 →
Ceramide Np
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Ceramide NP (N-Acylated Phytosphingosine)
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Ceramide Np
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
The Design and Optimization of Ceramide NP-Loaded Liposomes to Restore the Skin Barrier.
Şahin Bektay H, Sağıroğlu AA, Bozali K, Güler EM, Güngör S
Pharmaceutics, 2023
→
The Effectiveness and Safety of a Skin Care Product With Centella asiatica Leaf Extract, Ceramide NP, and Panthenol in Subjects With Sensitive Skin: A
Su Z, Zheng Y, Yi J, Lai W, Ye C
Journal of cosmetic dermatology, 2025
→
The Effectiveness and Safety of a Skin Care Product With Centella asiatica Leaf Extract, Ceramide NP, and Panthenol in Subjects With Sensitive Skin: A
Su Z, Zheng Y, Yi J, Lai W, Ye C
Journal of cosmetic dermatology, 2025
→
Verified Feb 2026
Data: CosIng · EWG · CIR