Ceramide np (N-acylated Phytosphingosine)
AKA “ceramide np, Ceramide 3B, Cytomide IIIa, Cytomide IIIb, Ceramide IIIB”
Synthetic
Ingredient Facts
Ceramide np (N-acylated Phytosphingosine)
AKA: Ceramide 3B, Cytomide IIIa, Cytomide IIIb, Ceramide IIIB
Synthetic · Emollient · EWG: 4
Synthetic
Emollient
Skin Conditioner
Ceramide
Synthetic
Clean
A naturally-derived moisturizer that strengthens your skin's barrier and leaves hair soft and smooth.
CAS #
72968-43-5
Form
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Moisturising
Strengthens skin barrier
Locks in moisture
Prevents moisture loss
Traditional Use
Developed in the 1990s as a synthetic ceramide designed to mimic natural ceramides found in skin barrier lipids. Ceramides were identified as key components of the stratum corneum, and synthetic versions were created to repair compromised skin barriers and reduce transepidermal water loss.
Skin Types
●all-skin-types
Best For
Dryness
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
Ceramide Np
European Commission
EU Cosmetic Ingredient Database (CosIng)
Ceramide NP (N-Acylated Phytosphingosine)
European Commission
EU Cosmetic Ingredient Database (CosIng)
Ceramide Np
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
The Design and Optimization of Ceramide NP-Loaded Liposomes to Restore the Skin Barrier.
Şahin Bektay H, Sağıroğlu AA, Bozali K, Güler EM, Güngör S
Pharmaceutics, 2023
The Effectiveness and Safety of a Skin Care Product With Centella asiatica Leaf Extract, Ceramide NP, and Panthenol in Subjects With Sensitive Skin: A
Su Z, Zheng Y, Yi J, Lai W, Ye C
Journal of cosmetic dermatology, 2025
The Effectiveness and Safety of a Skin Care Product With Centella asiatica Leaf Extract, Ceramide NP, and Panthenol in Subjects With Sensitive Skin: A
Su Z, Zheng Y, Yi J, Lai W, Ye C
Journal of cosmetic dermatology, 2025
Verified Feb 2026
Data: CosIng · EWG · CIR