Choline Chloride
AKA “Lipotril, N-trimethylethanaminium chloride, Hepacholine, Paresan, (2-Hydroxyethyl)trimethylammonium chloride, Hormocline, Biocolina, Biocoline
Synthetic
Ingredient Facts
Choline chloride
AKA: Lipotril, N-trimethylethanaminium chloride, Hepacholine, Paresan, (2-Hydroxyethyl)trimethylammonium chloride, Hormocline, Biocolina, Biocoline
Synthetic · Humectant · EWG: 4
Synthetic
Humectant
Skin Conditioner
Synthetic
Clean
A natural humectant that draws moisture into skin and helps maintain hydration, leaving it soft and supple.
Solubility Very soluble (NTP, 1992)
Formula
C5H14ClNO
Mol. Weight
139.62
CAS #
67-48-1
Form
Liquid
State
Choline chloride appears as white crystals. Practically neutral aqueous solution. (NTP, 1992)
See origin →
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks In Moisture
Traditional Use
Choline was identified as an essential nutrient in the early 20th century. Choline chloride is used in cosmetics for its hydrating and cell-regulating properties, supporting skin barrier function.
Skin Types
all-skin-types
Best For
Dehydration
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
ewg-4
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUpermitted
JAPANpermitted
CANADApermitted
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR