Diethyl Sebacate
AKA “Diethyl decanedioate, Ethyl sebacate, Decanedioic acid, diethyl ester, Bisoflex DES, Sebacic acid, Sebacic acid diethyl ester
Synthetic
Ingredient Facts
Diethyl sebacate
AKA: Diethyl decanedioate, Decanedioic acid, Diethyl ester, Bisoflex DES, Sebacic acid, Sebacic acid diethyl ester
Synthetic · Emollient · EWG: 4
Synthetic
Emollient
Solvent
Skin Conditioner
Plant Oil
Synthetic
Clean
A lightweight conditioning agent that softens skin and helps formulas stay smooth and blendable. Keeps products from becoming sticky or greasy.
Solubility 0.08 mg/mL at 20 °C
Formula
C14H26O4
Mol. Weight
258.35
CAS #
110-40-7
Form
Liquid
State
Colorless to yellowish liquid; [Merck Index] Clear colorless liquid; [Sigma-Aldrich MSDS]
See origin →
Functions
Plasticiser
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks In Moisture
Traditional Use
Synthetic ester developed for cosmetic use as a conditioning and emollient agent. Created to replace traditional plant-derived oils in formulations requiring specific chemical stability.
Skin Types
all-skin-types
Best For
Dryness
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Capryloyl Glycerin/Sebacic Acid Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
Diethyl Sebacate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Dodecanedioic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Propylene Glycol/Sebacic Acid/Trimellitic Anhydride Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
Sebacic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Capryloyl Glycerin/Sebacic Acid Copolymer
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Diethyl Sebacate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Sebacic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Antitumor efficacy of poly(dimer acid-dodecanedioic acid) copolymer in mice bearing Sarcoma-180 tumor.
Guo WX, Shi Z, Zeng FB, Liang K, Chen XH et al.
Journal of materials science. Materials in medicine, 2007
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR