Diethylhexyl Sebacate
AKA “Di-n-octyl sebacate, Dioctyl sebacate, Dioctyl decanedioate, Decanedioic acid, dioctyl ester, Witamol 500, Sebacic acid
Synthetic
Ingredient Facts
Diethylhexyl sebacate
AKA: Di-n-octyl sebacate, Dioctyl sebacate, Dioctyl decanedioate, Decanedioic acid, Dioctyl ester, Witamol 500, Sebacic acid
Synthetic · Emollient · EWG: 4
Synthetic
Emollient
Occlusive
Solvent
Skin Conditioner
Synthetic
Clean
Lightweight emollient that smooths skin and helps products glide on effortlessly while creating a protective layer that locks in moisture.
Formula
C26H50O4
Mol. Weight
426.70
CAS #
122-62-3
Form
Powder
See origin →
Functions
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Plasticiser
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks In Moisture
Traditional Use
Synthetic ester developed for cosmetics as a lightweight emollient and conditioning agent. Created to provide improved absorption and skin feel compared to heavier traditional oils.
Skin Types
all-skin-types
Best For
Dryness
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Capryloyl Glycerin/Sebacic Acid Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
Diethylhexyl Sebacate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Dodecanedioic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Propylene Glycol/Sebacic Acid/Trimellitic Anhydride Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
Sebacic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Capryloyl Glycerin/Sebacic Acid Copolymer
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Diethylhexyl Sebacate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Sebacic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Antitumor efficacy of poly(dimer acid-dodecanedioic acid) copolymer in mice bearing Sarcoma-180 tumor.
Guo WX, Shi Z, Zeng FB, Liang K, Chen XH et al.
Journal of materials science. Materials in medicine, 2007
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR