Dihexyl Adipate
AKA “Dihexyl hexanedioate, Hexanedioic acid, dihexyl ester, Di-n-hexyl adipate, Adipic acid, Plasticizer dihexyl adipate, EINECS 203-757-7”
Synthetic
Ingredient Facts
Dihexyl adipate
AKA: Dihexyl hexanedioate, Hexanedioic acid, Dihexyl ester, Di-n-hexyl adipate, Adipic acid, Plasticizer dihexyl adipate, EINECS 203-757-7
Synthetic · Emollient · EWG: 4
Synthetic
Emollient
Solvent
Skin Conditioner
Synthetic
Clean
A lightweight emollient that softens and conditions skin, helping products glide on smoothly while maintaining moisture balance.
Formula
C18H34O4
Mol. Weight
314.50
CAS #
110-33-8
Form
Liquid
State
Di-n-hexyl adipate is a colorless liquid. Floats on water. (USCG, 1999)
See origin →
Functions
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks In Moisture
Traditional Use
Synthetic ester developed in cosmetic chemistry as a non-greasy emollient. Created to mimic the skin-conditioning properties of plant oils while offering better oxidative stability.
Skin Types
●all-skin-types
Best For
Dryness
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
Final Report on the Safety Assessment of Adipic Acid Dihydrazide
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
1,4-Butanediol/Succinic Acid/Adipic Acid/HDI Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
Adipic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Adipic Acid/CHDM/MA/Neopentyl Glycol/Trimellitic Anhydride Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
Adipic Acid/Neopentyl Glycol/Trimellitic Anhydride Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
Dihexyl Adipate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Trimethylpentanediol/Adipic Acid/Glycerin Crosspolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
Adipic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Adipic Acid/Neopentyl Glycol/Trimellitic Anhydride Copolymer
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Trimethylpentanediol/Adipic Acid/Glycerin Crosspolymer
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Toxicity of adipic acid.
Kennedy GL Jr
Drug and chemical toxicology, 2002
Allergic Contact Dermatitis to Trimethylpentanediol/Adipic Acid/Glycerin Crosspolymer in a Lip Balm.
Lockmann A, Schill T, Schubert S, Buhl T
Contact dermatitis, 2026
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR