Diisocetyl Dodecanedioate
AKA “
UNII-1116DS0SNT, Dodecanedioic acid, diisohexadecyl ester, 12-diisohexadecyl ester, RefChem:134043, DIISOCETYL DODECANEDIOATE [INCI], bis(14-methylpentadecyl) dodecanedioate
”
Synthetic
🦆
❤️
👻
Ingredient Facts
Diisocetyl dodecanedioate
AKA: UNII-1116DS0SNT, Dodecanedioic acid, Diisohexadecyl ester, 12-diisohexadecyl ester, RefChem:134043, DIISOCETYL DODECANEDIOATE [INCI], Bis(14-methylpentadecyl) dodecanedioate
Synthetic · Emollient · EWG: 4
WHAT IS IT?
Synthetic
Emollient
Cleanser
Emulsifier
Skin Conditioner
Synthetic
Clean
A lightweight emollient that softly conditions skin while helping cleanse and blend product textures together for a smooth, unified formula.
Formula
C44H86O4
Mol. Weight
679.10
CAS #
131252-83-0
Form
Liquid
See origin →
WHAT'S IT DO?
Functions
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Locks In Moisture
Traditional Use
Modern synthetic ester created for premium cosmetic conditioning. Formulated to provide superior skin feel and moisturization.
Skin Types
●
all-skin-types
Best For
Dryness
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
IS IT SAFE?
EWG
4
CIR
Insufficient
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA
under review
EU
⚠ restricted
JAPAN
⚠ restricted
CANADA
⚠ restricted
Regulatory Agencies
EWG
CIR
FDA
EU COSING
Health Canada
WHAT'S THE PROOF?
Diisocetyl Dodecanedioate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Dodecanedioic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Antitumor efficacy of poly(dimer acid-dodecanedioic acid) copolymer in mice bearing Sarcoma-180 tumor.
Guo WX, Shi Z, Zeng FB, Liang K, Chen XH et al.
Journal of materials science. Materials in medicine, 2007
→
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR