Dioctyl Adipate
AKA “Dioctyl hexanedioate, Di-n-octyl adipate, Hexanedioic acid, dioctyl ester, Dicaprylyl adipate, Adipic acid, 6-dioctyl hexanedioate”
Synthetic
Ingredient Facts
Dioctyl adipate
AKA: Dioctyl hexanedioate, Di-n-octyl adipate, Hexanedioic acid, Dioctyl ester, Dicaprylyl adipate, Adipic acid, 6-dioctyl hexanedioate
Synthetic · Emollient · EWG: 4
Synthetic
Emollient
Skin Conditioner
Synthetic
Clean
A lightweight emollient that softens and smooths skin while helping the product glide on effortlessly and absorb quickly.
Solubility INSOL IN WATER @ 25 °C; INSOL OR VERY SLIGHTLY SOL IN GLYCERINE & GLYCOLS; SOL IN MOST ORGANIC SOLVENTS
Formula
C22H42O4
Mol. Weight
370.60
CAS #
123-79-5
Form
Oil
State
Liquid
See origin →
Functions
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Viscosity Controlling
Traditional Use
A synthetic plasticizer and emollient developed in the 20th century. Used in cosmetics to improve product texture and skin feel; has no traditional history.
Skin Types
●all-skin-types
Best For
Dryness
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Caution
Final Report on the Safety Assessment of Adipic Acid Dihydrazide
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of Dioctyl Adipate and Diisopropyl Adipate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
1,4-Butanediol/Succinic Acid/Adipic Acid/HDI Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
Adipic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Adipic Acid/CHDM/MA/Neopentyl Glycol/Trimellitic Anhydride Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
Adipic Acid/Neopentyl Glycol/Trimellitic Anhydride Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
Trimethylpentanediol/Adipic Acid/Glycerin Crosspolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
Adipic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Adipic Acid/Neopentyl Glycol/Trimellitic Anhydride Copolymer
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Trimethylpentanediol/Adipic Acid/Glycerin Crosspolymer
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Toxicity of adipic acid.
Kennedy GL Jr
Drug and chemical toxicology, 2002
Allergic Contact Dermatitis to Trimethylpentanediol/Adipic Acid/Glycerin Crosspolymer in a Lip Balm.
Lockmann A, Schill T, Schubert S, Buhl T
Contact dermatitis, 2026
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR