Disodium Azelate
AKA “azelaic acid, disodium salt, RefChem:135012, disodium;nonanedioate, Nonanedioic acid, disodium nonanedioate
Synthetic
Ingredient Facts
Disodium azelate
AKA: Azelaic acid, Disodium salt, RefChem:135012, Disodium;nonanedioate, Nonanedioic acid, Disodium nonanedioate
Synthetic · Skin Conditioning · EWG: 4
Synthetic
Skin Conditioner
Synthetic
Clean
A lightweight texture enhancer that gives products the perfect consistency—not too thick, not too thin—for easy application.
Formula
C9H14Na2O4
Mol. Weight
232.18
CAS #
17265-13-3, 27825-99-6, 132499-85-5
Form
Powder
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Viscosity Controlling
Controls Viscosity
Antioxidant Protection
Traditional Use
The sodium salt of azelaic acid derived from cereal grains and yeast. Azelaic acid has been used in modern dermatology since the 1980s for treating acne and hyperpigmentation.
Skin Types
all-skin-types
Best For
Acne
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Insufficient
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USAunder review
EUrestricted
JAPANrestricted
CANADArestricted
Disodium Azelate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Azelaic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Azelaic acid and its salts
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Topical azelaic acid, salicylic acid, nicotinamide, sulph...
Haibo Liu, Haiyan Yu, Jun Xia, Ling Liu, Guan J Liu, Hong Sang + 1 more
The Cochrane database of systematic reviews, 2020
Topical azelaic acid, salicylic acid, nicotinamide, sulph...
Haibo Liu, Haiyan Yu, Jun Xia, Ling Liu, Guan J Liu, Hong Sang + 1 more
The Cochrane database of systematic reviews, 2020
Topical azelaic acid, salicylic acid, nicotinamide, sulph...
Haibo Liu, Haiyan Yu, Jun Xia, Ling Liu, Guan J Liu, Hong Sang + 1 more
The Cochrane database of systematic reviews, 2020
Topical azelaic acid, salicylic acid, nicotinamide, sulph...
Haibo Liu, Haiyan Yu, Jun Xia, Ling Liu, Guan J Liu, Hong Sang + 1 more
The Cochrane database of systematic reviews, 2020
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne.
Liu H, Yu H, Xia J, Liu L, Liu GJ et al.
The Cochrane database of systematic reviews, 2020
The versatility of azelaic acid in dermatology.
Tamara Searle, Faisal R Ali, Firas Al-Niaimi
The Journal of dermatological treatment, 2022
The versatility of azelaic acid in dermatology.
Tamara Searle, Faisal R Ali, Firas Al-Niaimi
The Journal of dermatological treatment, 2022
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR