Disodium Glycyrrhizate
AKA “Disodium glycyrrhizin, UNII-L8Q0US0J7V, CCRIS 1966, Glycyrrhizinic acid disodium salt, DISODIUM GLYCYRRHIZATE [WHO-DD], alpha-D-Glucopyranosiduronic acid, (3-beta, disodium salt
Synthetic
Ingredient Facts
Disodium glycyrrhizate
AKA: Disodium glycyrrhizin, UNII-L8Q0US0J7V, CCRIS 1966, Glycyrrhizinic acid disodium salt, DISODIUM GLYCYRRHIZATE [WHO-DD], Alpha-D-Glucopyranosiduronic acid, (3-beta, Disodium salt
Synthetic · Antioxidant · EWG: 4
Synthetic
Antioxidant
Soothing
Skin Conditioner
Synthetic
Clean
Derived from licorice root, this ingredient soothes and conditions skin, helping to calm irritation and improve overall skin comfort.
Formula
C42H59Na2O16-
Mol. Weight
865.90
CAS #
71277-79-7
Form
Powder
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Soothing
Calms redness, irritation, and inflammation. Your skin's chill pill — great for sensitive, reactive, or post-procedure skin.
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Brightens uneven skin tone
Evens pigmentation
Quells irritation
Traditional Use
Derived from licorice root (used for over 4,000 years in Traditional Chinese Medicine and Ayurveda); the disodium salt form was developed to provide anti-inflammatory and skin-soothing benefits in modern cosmetics.
Skin Types
all-skin-types
Best For
Redness
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
Not an Irritant
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR