Ethanolamine Thioglycolate
AKA “Monoethanolamine thioglycolate, (2-Hydroxyethyl)ammonium mercaptoacetate, EINECS 204-815-4, EC 204-815-4, THIOGLYCOLIC ACID MONOETHANOLAMINE SALT, N-(2-HYDROXYETHYL)AMMONIUM THIOGLYCOLATE
Synthetic
Ingredient Facts
Ethanolamine thioglycolate
AKA: Monoethanolamine thioglycolate, (2-Hydroxyethyl)ammonium mercaptoacetate, EINECS 204-815-4, EC 204-815-4, THIOGLYCOLIC ACID MONOETHANOLAMINE SALT, N-(2-HYDROXYETHYL)AMMONIUM THIOGLYCOLATE
Synthetic · Depilatory · EWG: 4
Synthetic
Synthetic
Clean
A professional-grade ingredient that breaks down hair structure for smooth removal or styling. Commonly used in hair removal and permanent wave treatments.
Formula
C4H11NO3S
Mol. Weight
153.20
CAS #
126-97-6
Form
Liquid
State
Liquid
See origin →
Functions
Depilatory
Hair Waving Or Straightening
Reducing
Reducing Agent
Wound Healing
Changes hair texture
Removes unwanted hair
Chemical reduction
Traditional Use
A synthetic reducing agent developed in the mid-20th century specifically for use in hair permanent wave solutions and depilatory products. Created to chemically alter protein bonds in hair and dissolve hair.
Skin Types
all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
No
EWG
4
CIR
Safe w/Qualifications
Pregnancy
No
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUpermitted
JAPANpermitted
CANADApermitted
Final amended report on the safety assessment of Ammonium Thioglycolate, Butyl Thioglycolate, Calcium Thioglycolate, Ethanolamine Thioglycolate, Ethyl
Burnett CL, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
Final amended report on the safety assessment of Ammonium Thioglycolate, Butyl Thioglycolate, Calcium Thioglycolate, Ethanolamine Thioglycolate, Ethyl
Burnett CL, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
Final amended report on the safety assessment of Ammonium Thioglycolate, Butyl Thioglycolate, Calcium Thioglycolate, Ethanolamine Thioglycolate, Ethyl
Burnett CL, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
Final amended report on the safety assessment of Ammonium Thioglycolate, Butyl Thioglycolate, Calcium Thioglycolate, Ethanolamine Thioglycolate, Ethyl
Burnett CL, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
Final amended report on the safety assessment of Ammonium Thioglycolate, Butyl Thioglycolate, Calcium Thioglycolate, Ethanolamine Thioglycolate, Ethyl
Burnett CL, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
Final amended report on the safety assessment of Ammonium Thioglycolate, Butyl Thioglycolate, Calcium Thioglycolate, Ethanolamine Thioglycolate, Ethyl
Burnett CL, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
Final amended report on the safety assessment of Ammonium Thioglycolate, Butyl Thioglycolate, Calcium Thioglycolate, Ethanolamine Thioglycolate, Ethyl
Burnett CL, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
Final amended report on the safety assessment of Ammonium Thioglycolate, Butyl Thioglycolate, Calcium Thioglycolate, Ethanolamine Thioglycolate, Ethyl
Burnett CL, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
Final Amended Report on the Safety Assessment of Ammonium Thioglycolate, Butyl Thioglycolate, Calcium Thioglycolate, Ethanolamine Thioglycolate, Ethyl Thioglycolate, Glyceryl Thioglycolate, Isooctyl T
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Ethanolamine Thioglycolate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR