Ethoxydiglycol
AKA “Diethylene glycol monoethyl ether, 2-(2-Ethoxyethoxy)ethanol, CARBITOL, Transcutol, Ethyl carbitol, Dioxitol, Ethoxy diglycol, Carbitol solvent
Synthetic
Ingredient Facts
Ethoxydiglycol
AKA: Diethylene glycol monoethyl ether, 2-(2-Ethoxyethoxy)ethanol, CARBITOL, Transcutol, Ethyl carbitol, Dioxitol, Ethoxy diglycol, Carbitol solvent
Synthetic · Humectant · EWG: 4
Synthetic
Humectant
Fragrance
Solvent
Synthetic
Clean
A hydrating ingredient that helps lock moisture into skin while enhancing the scent and texture of the formula.
Solubility greater than or equal to 100 mg/mL at 68 °F (NTP, 1992)
Formula
C6H14O3
Mol. Weight
134.17
CAS #
111-90-0
Form
Liquid
State
Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190 °F. Used to make soaps, dyes, and other chemicals.
See origin →
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Perfuming
Added for scent. Can be natural or synthetic. Common irritant and allergen — one of the top reasons people react to products.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks In Moisture
Traditional Use
A synthetic humectant and solvent created in the 20th century. Developed as an alternative to glycerin and propylene glycol, designed to absorb moisture and improve product texture in skincare formulations.
Skin Types
all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Concentration Guide
2.6%
0%4%
Reg. Limit
SCCS maximum safe concentration: 2.6%. Product type: rinse-off, non-oxidative. Source: SCCS Opinion SCCS/1507/13.
Regulatory Status
USApermitted
EUpermitted
JAPANpermitted
CANADApermitted
Enhanced skin permeation of a new capsaicin derivative (DA-5018) from a binary vehicle system composed of isopropyl myristate and ethoxydiglycol.
Cha BJ, Lee ED, Kim WB, Chung SJ, Lee MH et al.
Archives of pharmacal research, 2001
Final Report on the Safety Assessment of Butylene Glycol, Hexylene Glycol, Ethoxydiglycol, and Dipropylene Glycol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Ethoxydiglycol
European Commission
EU Cosmetic Ingredient Database (CosIng)
Methoxydiglycol Methacrylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Ethoxydiglycol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Methoxydiglycol
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Permeation Enhancer in Microemulsions and Microemulsion-Based Gels: A Comparison of Diethylene Glycol Monoethyl Ether and Oleyl Alcohol.
Pandey S, Baki G
Gels (Basel, Switzerland), 2025
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR
Ethoxydiglycol — Duck Heart Ghost