Glutaric Acid
AKA “Pentanedioic acid, 5-Pentanedioic acid, glutarate, 3-Propanedicarboxylic acid, Pentandioic acid, n-Pyrotartaric acid
Synthetic
Ingredient Facts
Glutaric acid
AKA: Pentanedioic acid, 5-Pentanedioic acid, Glutarate, 3-Propanedicarboxylic acid, Pentandioic acid, N-Pyrotartaric acid
Synthetic · Buffering · EWG: 4
Synthetic
Synthetic
Clean
Helps maintain the product's ideal pH balance, keeping the formula stable and effective on skin.
Solubility greater than or equal to 100 mg/mL at 70 °F (NTP, 1992)
Formula
C5H8O4
Mol. Weight
132.11
CAS #
110-94-1
Form
Liquid
State
Glutaric acid appears as colorless crystals or white solid. (NTP, 1992)
See origin →
Functions
Buffering
pH Adjusting
Stabilizes pH
Anti-Aging Benefits
Antioxidant Protection
Reduces Inflammation
Traditional Use
A synthetic organic acid developed for industrial purposes in the 20th century. It was later incorporated into cosmetics as a pH buffer and preservative booster with no traditional use history.
Skin Types
all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
RIFM fragrance ingredient safety assessment, pentanedioic acid, 1,5-dimethyl ester, CAS Registry Number 1119-40-0.
Api AM, Belsito D, Botelho D, Browne D, Bruze M et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018
Diisobutyl Glutarate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Diisostearyl Glutarate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Dimethyl Glutarate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glutaric Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Riboflavin-responsive lipid-storage myopathy and glutaric aciduria type II of early adult onset.
de Visser M, Scholte HR, Schutgens RB, Bolhuis PA, Luyt-Houwen IE et al.
Neurology, 1986
Dimethyl Glutarate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR