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glutathione
AKA “L-Glutathione, L-Glutathione reduced, Glutathion, Isethion, reduced glutathione, Tathion, Glutinal, Glutathione-SH”
Peptide
Ingredient Facts
glutathione
AKA: L-Glutathione, L-Glutathione reduced, Isethion, Reduced glutathione, Glutinal, Glutathione-SH
Peptide · Antioxidant · EWG: 1
Synthetic
Antioxidant
Skin Conditioner
Amino Acid
Peptide
Clean
A powerful antioxidant that helps protect skin from environmental damage and supports a brighter, more radiant complexion.
Formula
C10H17N3O6S
Mol. Weight
307.33
CAS #
70-18-8
Form
Powder
See origin →
Functions
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Reducing
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Brightening
Evens out dull skin tone for a more radiant, lit-from-within look
Antimicrobial
Provides scent
Chemical reduction
Traditional Use
This appears to be a CAS number without a standard cosmetic INCI name; unable to provide historical context without clarification of the specific ingredient.
Skin Types
●all-skin-types, gentle
Best For
General
Melanin-Rich Skin
Suitable
EWG
1
CIR
Insufficient
Pregnancy
—
CIR Safety Findings
ewg-1
pregnancy-nursing-safe
all-shades-safe
Regulatory Status
USAunder review
CANADA✔ permitted
Regulatory Agencies
Hexamidine and Hexamidine Diisethionate.
Cherian P, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2023
→
Amended Safety Assessment of Isethionate Salts as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Hexamidine and Hexamidine Diisethionate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Sodium Cocoyl Isethionate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Hexamidine and Hexamidine Diisethionate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Ammonium Cocoyl Isethionate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
glutathione
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Hexamidine Diisethionate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Cocoyl Isethionate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Hydrogenated Cocoyl Methyl Isethionate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Isethionate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Lauroyl Isethionate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Lauroyl Methyl Isethionate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Methyl Isethionate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Myristoyl Isethionate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Oleoyl Isethionate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Oleyl Methyl Isethionate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Palm Kerneloyl Isethionate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Stearoyl Methyl Isethionate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Engineering Yarrowia lipolytica for the Synthesis of Glutathione from Organic By-Products.
Do DTH, Fickers P
Microorganisms, 2020
→
FSP1 is a glutathione-independent ferroptosis suppressor.
Doll S, Freitas FP, Shah R, Aldrovandi M, da Silva MC et al.
Nature, 2019
→
FSP1 is a glutathione-independent ferroptosis suppressor.
Doll S, Freitas FP, Shah R, Aldrovandi M, da Silva MC et al.
Nature, 2019
→
Ammonium Cocoyl Isethionate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
glutathione
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Hexamidine Diisethionate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sodium Cocoyl Isethionate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sodium Isethionate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sodium Lauroyl Isethionate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sodium Lauroyl Methyl Isethionate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sodium Methyl Isethionate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Why is sodium cocoyl isethionate (SCI) mild to the skin barrier? - An in vitro investigation based on the relative sizes of the SCI micelles and the s
Ghosh S, Blankschtein D
Journal of cosmetic science, 2007
→
Glutathione as a skin whitening agent: Facts, myths, evid...
Sidharth Sonthalia, Deepashree Daulatabad, Rashmi Sarkar
Indian journal of dermatology, venereology and leprology, 2016
→
Glutathione as a skin whitening agent: Facts, myths, evid...
Sidharth Sonthalia, Deepashree Daulatabad, Rashmi Sarkar
Indian journal of dermatology, venereology and leprology, 2016
→
Glutathione as a skin whitening agent: Facts, myths, evid...
Sidharth Sonthalia, Deepashree Daulatabad, Rashmi Sarkar
Indian journal of dermatology, venereology and leprology, 2016
→
Glutathione as a skin whitening agent: Facts, myths, evidence and controversies.
Sonthalia S, Daulatabad D, Sarkar R
Indian journal of dermatology, venereology and leprology, 2016
→
Solubilization of sodium cocoyl isethionate.
Sun JZ, Parr JW, Erickson MC
Journal of cosmetic science, 2003
→
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR